Allergy Research Group Tricycline GI Microbial Support
Product Description
Tricycline® delivers traditional and evidence-based botanicals including berberine, artemisinin, citrus seed extract, black walnut, and sweet wormwood to support a healthy intestinal microbiome and digestive function.* Ideal for complementary use with probiotics.* The grapefruit seed extract we use has been shown via third-party testing to be free of the potentially dangerous contaminants triclosan, benzethonium chloride, and benzalkonium chloride.*
Ingredients:
Other Ingredients:
If you are trying to conceive, taking any medications, or have a medical condition, please consult your healthcare practitioner before using this product.
Keep out of reach of children.
Support Balanced Microbial Ecology in the GI Tract*
What It Does
Tricycline® is a microbial balancing formula designed to support a healthy gastrointestinal (GI) microbiome.* It complements probiotic use by promoting a balanced microbial environment and healthy intestinal function.* This unique botanical blend offers targeted support for digestive health and intestinal microbial ecology.*
How It Works
• Berberine: A bioactive alkaloid that supports digestive function and modulates the gut microbiome toward a favorable balance, encouraging short-chain fatty acid production and healthy mucosal integrity.*[1]
• Artemisinin (from Artemisia annua): A highly concentrated form of sweet wormwood shown to influence GI microbial composition via multiple mechanisms; independently tested for cell activity and potency via third-party HPLC.*[4]
• Citrus Seed Extract (Grapefruit): Contains polyphenols such as naringenin, which may influence gut motility and intestinal barrier function while promoting microbial diversity in the proximal colon.*[5-7]
• Black Walnut Hulls: Traditionally used to support skin and GI health; a source of tannins and antioxidant compounds with microbial-modulating effects.*[8]
• Sweet Wormwood (Artemisia annua): A traditional herb used for microbial balance, providing additional phytochemical support to the artemisinin content.*
Who It’s For
Ideal for individuals seeking additional gastrointestinal support beyond probiotics, particularly those with concerns about microbial balance, gut motility, or intestinal immune tone.*
Special Features
Tricycline® features independently verified artemisinin potency, third-party HPLC testing, and a comprehensive blend of traditional and modern microbiome-focused botanicals. It is formulated without unnecessary fillers or allergens.
References
1. Xu X, et al. Biomed Pharmacother. 2021;133:110984. doi:10.1016/j.biopha.2020.110984
2. Caliceti C, et al. Curr Med Chem. 2016;23(14):1460-76.
3. Zhang L, et al. Front Cell Infect Microbiol. 2021;10:588517. doi:10.3389/fcimb.2020.588517
4. Golenser J, et al. Int J Parasitol. 2006;36(14):1427-41.
5. Sost MM, et al. Nutrients. 2021;13(11):3915. https://doi.org/10.3390/nu13113915
6. Wu L, et al. Foods. 2024;13(16):2520. https://doi.org/10.3390/foods13162520
7. Stevens Y, et al. Nutrients. 2019;11(7):1464. https://doi.org/10.3390/nu11071464
8. Jahanban-Esfahlan A, et al. Int J Mol Sci. 2019;20(16):3920. doi:10.3390/ijms20163920
9. Wenzel J, et al. Food Sci Nutr. 2016;5(2):223-32.
